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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNA5
All Species:
23.33
Human Site:
Y179
Identified Species:
51.33
UniProt:
P22460
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22460
NP_002225.2
613
67228
Y179
F
D
G
I
L
Y
Y
Y
Q
S
G
G
R
L
R
Chimpanzee
Pan troglodytes
XP_522330
602
66099
Y168
F
D
G
I
L
Y
Y
Y
Q
S
G
G
R
L
R
Rhesus Macaque
Macaca mulatta
XP_001102294
605
66481
Y168
F
D
G
I
L
Y
Y
Y
Q
S
G
G
R
L
R
Dog
Lupus familis
XP_543859
495
56374
S114
N
V
P
L
D
M
F
S
E
E
I
K
F
Y
E
Cat
Felis silvestris
Mouse
Mus musculus
Q61762
602
66626
Y170
F
D
G
I
L
Y
Y
Y
Q
S
G
G
R
L
R
Rat
Rattus norvegicus
P19024
602
66534
Y170
F
D
G
I
L
Y
Y
Y
Q
S
G
G
R
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508339
499
56706
G119
E
I
R
F
Y
E
L
G
E
E
A
M
E
M
F
Chicken
Gallus gallus
Q7T199
516
58965
F136
S
M
R
N
E
Y
F
F
D
R
N
R
P
S
F
Frog
Xenopus laevis
P22739
499
56683
G119
E
I
R
F
Y
E
L
G
E
E
A
M
E
I
F
Zebra Danio
Brachydanio rerio
XP_001922996
515
58572
V134
G
G
R
I
R
R
P
V
N
V
P
I
D
I
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P08510
655
74175
Y156
F
D
A
I
L
Y
Y
Y
Q
S
G
G
R
L
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.8
97.2
55.9
N.A.
84.3
86.1
N.A.
58
53.1
56.6
57.7
N.A.
51.7
N.A.
N.A.
N.A.
Protein Similarity:
100
98
97.5
65
N.A.
87.9
89
N.A.
65.2
63.7
64.4
66.3
N.A.
63.6
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
0
N.A.
100
100
N.A.
0
6.6
0
6.6
N.A.
93.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
20
N.A.
100
100
N.A.
13.3
20
13.3
13.3
N.A.
93.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
0
0
19
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
55
0
0
10
0
0
0
10
0
0
0
10
0
0
% D
% Glu:
19
0
0
0
10
19
0
0
28
28
0
0
19
0
10
% E
% Phe:
55
0
0
19
0
0
19
10
0
0
0
0
10
0
37
% F
% Gly:
10
10
46
0
0
0
0
19
0
0
55
55
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
19
0
64
0
0
0
0
0
0
10
10
0
19
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% K
% Leu:
0
0
0
10
55
0
19
0
0
0
0
0
0
55
0
% L
% Met:
0
10
0
0
0
10
0
0
0
0
0
19
0
10
0
% M
% Asn:
10
0
0
10
0
0
0
0
10
0
10
0
0
0
0
% N
% Pro:
0
0
10
0
0
0
10
0
0
0
10
0
10
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
55
0
0
0
0
0
0
% Q
% Arg:
0
0
37
0
10
10
0
0
0
10
0
10
55
0
55
% R
% Ser:
10
0
0
0
0
0
0
10
0
55
0
0
0
10
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
10
0
0
0
0
0
10
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
19
64
55
55
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _